The notion that different diseases differ in their optical effect will be simulated in the present study through the use of different types of artificial stimulus degradation, in particular dioptric and gaussian blur. With gaussian blur, VEP acuity, psychophysical grating acuity, and psychophysical Landolt C acuity is expected to show better agreement than with dioptric blur. With the latter, VEP acuity and psychophysical grating acuity is expected to deviate from psychophysical Landolt C acuity.